Factorization homology is a homology theory for structured manifolds (e.g. oriented or parallelized) which finds its roots in topological and conformal field theory (cf. Beilinson–Drinfeld, Salvatore, Lurie, Ayala–Francis, Costello–Gwilliam among others). After defining factorization homology, I will explain how to compute it for simply connected closed manifolds over the real numbers using the Lambrechts–Stanley model of configuration spaces.